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Article

Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell lines

15 May 1997

Abstract excerpt

BACKGROUND: Progesterone (PROG) has been shown to reduce the risk of developing ovarian carcinoma in postmenopausal women who have undergone estrogen and progestogen replacement therapy, and it has been clinically used to treat some types of ovarian tumors. It is not yet clear whether or not the antitumor activity of progestogen is due to its ability to induce apoptosis in precarcinomatous and carcinomatous...

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Identifiers

PMID: 9149021
DOI: 10.1002/(sici)1097-0142(19970515)79:10<1944::aid-cncr15>3.0.co;2-v

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Source receipt: pubmed, retrieved 7 Sept 2026.

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