Article

Progesterone Activates a Progesterone Receptor Membrane Component 1-Dependent Mechanism That Promotes Human Granulosa/Luteal Cell Survival But Not Progesterone Secretion

2009-07-01

Abstract excerpt

Context: Progesterone (P4) promotes its own secretion and the survival of human granulosa/luteal (GL) cells. Objective: The objective of these studies was to determine whether progesterone receptor membrane component-1 (PGRMC1) mediates P4’s actions. Design:In vitro studies were conducted on GL cells from women undergoing in vitro fertilization and GL5 cells, which are derived from GL cells. Setting and Patients:...

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Literature Corpus work: 3363535c-e793-5b31-a69b-cd6c2fb5d45f
DOI: 10.1210/mend.23.7.9998

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