Article
The role of apoptosis in gynaecological malignancies.
Annals of medicine - 1 Apr 1997
Sheets E E, Yeh J
Abstract excerpt
Apoptosis is a process of single-cell deletion requiring active participation of the cell in its own demise. First described in 1972, it is now known to play a major role in embryogenesis, tissue homeostasis and neoplasia. Apoptosis can be initiated when DNA damage occurs causing the cell to pause in its reproductive cycle. If the DNA damage is beyond repair, the cell proceeds to apoptotic cell death. When the...
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