Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retinoic Acid Receptor β Expression and Growth Inhibition of Gynecologic Cancer Cells by the Synthetic Retinoid N-(4-Hydroxyphenyl) Retinamide

15 Apr 1998

Abstract excerpt

BACKGROUND: The synthetic retinoid N-(4-hydroxyphenyl) retinamide (4HPR) can inhibit the growth of tumor cells. Preliminary results from a clinical trial suggest that 4HPR may reduce ovarian cancer incidence. We examined the growth-inhibitory effects of 4HPR on gynecologic cancer cell lines in vitro and the role of retinoid receptors in modulating this effect. METHODS: Twelve human gynecologic cancer cell lines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Estrogen and related hormone effects
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9554442
DOI: 10.1093/jnci/90.8.597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retinoic Acid Receptor β Expression and Growth Inhibition of Gynecologic Cancer Cells by the Synthetic Retinoid N-(4-Hydroxyphenyl) RetinamidePMID 9554442Read ↗

Effects of retinoids on cancerous phenotype and apoptosis in organotypic cultures of ovarian carcinoma.Semantic proximity Read ↗

Synthetic retinoids as inducers of apoptosis in ovarian carcinoma cell lines.Semantic proximity Read ↗

Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expressionSemantic proximity Read ↗

Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cellsSemantic proximity Read ↗

Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.Semantic proximity Read ↗

N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells.Semantic proximity Read ↗

Effects of retinoic acid on cell differentiation and reversion toward normal in human endometrial adenocarcinoma (RL95-2) cells.Semantic proximity Read ↗

Ovarian Carcinoma Cell Cultures Are Resistant to TGF-β1-Mediated Growth Inhibition Despite Expression of Functional ReceptorsSemantic proximity Read ↗

4-Oxo-Fenretinide, a Recently Identified Fenretinide Metabolite, Induces Marked G2-M Cell Cycle Arrest and Apoptosis in Fenretinide-Sensitive and Fenretinide-Resistant Cell LinesSemantic proximity Read ↗

Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cellsSemantic proximity Read ↗

Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype.Semantic proximity Read ↗

Retinoic Acid and Retinoid X Receptors Are Differentially Expressed in Thyroid Cancer and Thyroid Carcinoma Cell Lines and Predict Response to Treatment with RetinoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.