Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

doi:10.1023/a:1025615409383

Back to search

Article

Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

Behavior genetics - 1 Jan 1997

Belknap J K, Richards S P, O'Toole L A, Helms M L, Phillips T J

Abstract excerpt

Short-term selective breeding starting from an F2 intercross of two inbred strains is a largely unexploited but potentially useful tool for quantitative trait locus (QTL) mapping. The selection lines can also serve as a valuable confirmation test of recombinant inbred (RI) QTL results when the sa...

Topics

Alcohol Drinking
Animals
Chromosome Mapping
Crosses, Genetic
Female
Gene Frequency
Genetic Markers
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Phenotype
Selection, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.