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Article

A method for mapping intralocus interactions influencing excessive alcohol drinking.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2010

Phillips Tamara J, Reed Cheryl, Burkhart-Kasch Sue, Li Na, Hitzemann Robert, Yu Chia-Hua, Brown Lauren L, Helms Melinda L, Crabbe John C, Belknap John K

Abstract excerpt

Excessive alcohol (ethanol) consumption is the hallmark of alcohol use disorders. The F1 hybrid cross between the C57BL/6J (B6) and FVB/NJ (FVB) inbred mouse strains consumes more ethanol than either progenitor strain. The purpose of this study was to utilize ethanol-drinking data and genetic information to map genes that result in overdominant (or heterotic) ethanol drinking. About 600 B6 x FVB F2 mice, half of...

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Identifiers

PMID: 20033183
DOI: 10.1007/s00335-009-9239-9
PMCID: PMC2850100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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