Article
Mapping of quantitative trait loci for ethanol preference in quasi-congenic strains.
Alcohol (Fayetteville, N.Y.) - 1 Feb 2000
Vadasz C, Saito M, Balla A, Kiraly I, Vadasz C, Gyetvai B, Mikics E, Pierson D, Brown D, Nelson J C
Abstract excerpt
Ethanol preference, a component of alcoholism, has been known for four decades to differ greatly between C57BL/6 and BALB/c inbred mouse strains. For mapping quantitative trait loci (QTLs) that affect ethanol preference, we used a set of B6.C Recombinant QTL Introgression (RQI) strains, which carry about 5% of the donor BALB/cJ (C) genome on a C57BL/6ByJ (B6) background. After characterizing males of the...
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