Mapping of quantitative trait loci for ethanol preference in quasi-congenic strains.

doi:10.1016/s0741-8329(99)00068-3

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Article

Mapping of quantitative trait loci for ethanol preference in quasi-congenic strains.

Alcohol (Fayetteville, N.Y.) - 1 Feb 2000

Vadasz C, Saito M, Balla A, Kiraly I, Vadasz C, Gyetvai B, Mikics E, Pierson D, Brown D, Nelson J C

Abstract excerpt

Ethanol preference, a component of alcoholism, has been known for four decades to differ greatly between C57BL/6 and BALB/c inbred mouse strains. For mapping quantitative trait loci (QTLs) that affect ethanol preference, we used a set of B6.C Recombinant QTL Introgression (RQI) strains, which carry about 5% of the donor BALB/cJ (C) genome on a C57BL/6ByJ (B6) background. After characterizing males of the...

Topics

Alcohol Drinking
Animals
Chromosome Mapping
Dopamine
Drinking
Ethanol
Female
Genotype
Male
Mice
Mice, Congenic
Mice, Inbred BALB C
Mice, Inbred C57BL
Phenotype
Species Specificity

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Open in PubMed

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PMID: 10719795
DOI: 10.1016/s0741-8329(99)00068-3

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