Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

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Article

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

Alcohol and alcoholism (Oxford, Oxfordshire). Supplement - 1 Jan 1994

Crabbe J C, Belknap J K, Buck K J, Metten P

Abstract excerpt

A recently-developed method of gene mapping is reviewed. Several responses to EtOH were studied with the purpose of identifying genes with modest effects (Quantitative Trait Loci, or QTLs). As an example, results from a study of acute ethanol withdrawal severity are discussed. Mice from inbred st...

Topics

Alleles
Animals
Chromosome Mapping
Crosses, Genetic
Ethanol
Female
Glutamate Decarboxylase
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Inbred Strains
Recombination, Genetic
Sodium Channels
Substance Withdrawal Syndrome

Source

Open in PubMed

Identifiers

PMID: 8974318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8974318-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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