Article
High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998
Metten P, Phillips T J, Crabbe J C, Tarantino L M, McClearn G E, Plomin R, Erwin V G, Belknap J K
Abstract excerpt
C57BL/6J (B6) inbred mice are well known to drink large amounts of alcohol (ethanol) voluntarily and to have only modest ethanol-induced withdrawal under fixed dose conditions. In contrast, DBA/2J (D2) mice are "teetotallers" and exhibit severe ethanol withdrawal. Speculation that an inverse gene...
Topics
- Alcohol Drinking
- Animals
- Ethanol
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Male
- Meta-Analysis as Topic
- Mice
- Mice, Inbred AKR
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mice, Inbred DBA