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Article

Discordance in p53 mutations when comparing ascites and solid tumors from patients with serous ovarian cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 1997

Provencher D M, Lounis H, Fink D, Drouin P, Mes-Masson A M

Abstract excerpt

We performed a mutational analysis of the p53 gene in matched samples of solid tumors and ascites from patients with ovarian cancer using the single-strand conformation polymorphism technique on exons 5-9 of the p53 gene on fresh and cultured material. We observed a discordance in the pattern of p53 mutations between the ascites and their solid tumor counterpart. In two cases, cancer cells from ascites carried a...

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Identifiers

PMID: 9143413
DOI: 10.1159/000218027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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