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Article

TP53 mutation in ovarian carcinoma.

European journal of cancer (Oxford, England : 1990) - 1 Jul 1997

Murphy M, McManus D T, Toner P G, Russell S E

Abstract excerpt

This short report describes the detection of mutations of the TP53 tumour suppressor gene in sporadic ovarian carcinomas using archival paraffin-embedded tissues and automated fluorescent DNA sequencing. TP53 mutations were detected in eight tumours. Missense mutations predominated and all were transitions. Mutations were commonest in late-stage serous tumours. In three cases, where tissue was available, the...

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PMID: 9301456
DOI: 10.1016/s0959-8049(97)00108-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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