Article
[Mutations of p53 gene exons 5 to 8 in human ovarian cancer and its clinical significance].
Zhonghua fu chan ke za zhi - 1 Nov 1996
You Z, Guo Y, Wen H
Abstract excerpt
OBJECTIVES: To detect p53 mutations in human ovarian cancer and to look for correlations between p53 mutation and clinicopathologic features. METHODS: Mutations in exons 5-8 of p53 gene in 41 patients with primary ovarian cancer were screened by polymerase chain reaction-single strand conformation polymorphism analysis with non-isotopic silver staining method. RESULTS: Mutations of p53 were found in 17 cases...
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