Article
Sources of variability in mutant frequency determinations in different organs of lacZ plasmid-based transgenic mice: experimental features and statistical analysis.
Environmental and molecular mutagenesis - 1 Jan 1997
Boerrigter M E, Vijg J
Abstract excerpt
Sources of variability that may affect the measurement of mutant frequencies in lacZ plasmid-based transgenic mice, including rescue-to-rescue, animal-to-animal (within organ), and organ-to-organ, were studied in the context of some of the experimental features that distinguish this model from ot...
Topics
- Animals
- Escherichia coli
- Lac Operon
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- Plasmids
- Sensitivity and Specificity
- Stem Cells