Article
Statistical design and analysis of mutation studies in transgenic mice.
Environmental and molecular mutagenesis - 1 Jan 1995
Carr G J, Gorelick N J
Abstract excerpt
We have been working on identifying sources of variability in data from transgenic mouse mutation assays in order to develop appropriate statistical methods and designs for routine studies. Data from our lab and elsewhere point to the presence of significant animal-to-animal variability, which mu...
Topics
- Animals
- Binomial Distribution
- Chi-Square Distribution
- Computer Simulation
- Cost-Benefit Analysis
- DNA
- Gene Expression Regulation
- Genetic Variation
- Liver
- Mice
- Mice, Transgenic
- Mutagenicity Tests
- Mutation
- Normal Distribution
- Sample Size