Article
Statistical tests of significance in transgenic mutation assays: considerations on the experimental unit.
Environmental and molecular mutagenesis - 1 Jan 1994
Carr G J, Gorelick N J
Abstract excerpt
When significant animal-to-animal variability is present in binary response data, the usual statistical tests applied to such data do not always operate correctly. In transgenic mouse mutation data, some evidence of significant animal-to-animal variability already exists, suggesting that conventi...
Topics
- Animals
- DNA Damage
- Data Interpretation, Statistical
- Dose-Response Relationship, Drug
- Liver
- Mice
- Mice, Transgenic
- Mutagenicity Tests
- Mutagens
- Mutation
- Species Specificity