Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue-Specific Expression of α and β Messenger Ribonucleic Acid Isoforms of the Human Mineralocorticoid Receptor in Normal and Pathological States

1 May 1997

Abstract excerpt

Expression of the mineralocorticoid receptor (MR) is restricted to some sodium-transporting epithelia and a few nonepithelial target tissues. Determination of the genomic structure of the human MR (hMR) revealed two different untranslated exons (1alpha and 1beta), which splice alternatively into the common exon 2, giving rise to two hMR mRNA isoforms (hMR alpha and hMR beta). We have investigated expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Hormonal Regulation and Hypertension
Share to Ion Transport and Channel Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9141514
DOI: 10.1210/jcem.82.5.3933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue-Specific Expression of α and β Messenger Ribonucleic Acid Isoforms of the Human Mineralocorticoid Receptor in Normal and Pathological StatesPMID 9141514Read ↗

Human Mineralocorticoid Receptor Genomic Structure and Identification of Expressed IsoformsSemantic proximity Read ↗

The Mineralocorticoid Receptor: Insights into its Molecular and (Patho)Physiological BiologySemantic proximity Read ↗

Characterization of the human mineralocorticoid receptor gene 5'-regulatory region: evidence for differential hormonal regulation of two alternative promoters via nonclassical mechanisms.Semantic proximity Read ↗

Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.Semantic proximity Read ↗

An alternatively spliced rat mineralocorticoid receptor mRNA causing truncation of the steroid binding domain.Semantic proximity Read ↗

Mineralocorticoid receptor splice variants in different human tissues.Semantic proximity Read ↗

A New Human MR Splice Variant Is a Ligand-Independent Transactivator Modulating Corticosteroid ActionSemantic proximity Read ↗

Targeted oncogenesis reveals a distinct tissue-specific utilization of alternative promoters of the human mineralocorticoid receptor gene in transgenic mice.Semantic proximity Read ↗

5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus.Semantic proximity Read ↗

Human mineralocorticoid receptor A and B protein forms produced by alternative translation sites display different transcriptional activitiesSemantic proximity Read ↗

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.Semantic proximity Read ↗

GLUCOCORTICOID AND MINERALOCORTICOID RECEPTORS: Biology and Clinical RelevanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.