Mineralocorticoid receptor splice variants in different human tissues.

doi:10.1530/eje.0.1380702

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Article

Mineralocorticoid receptor splice variants in different human tissues.

European journal of endocrinology - 1 Jun 1998

Wickert L, Watzka M, Bolkenius U, Bidlingmaier F, Ludwig M

Abstract excerpt

The mineralocorticoid receptor (MR), a member of the steroid receptor family, acts as a transcription factor and mediates both aldosterone and cortisol effects. Aldosterone specificity in some tissues results from the inactivation of competing cortisol into cortisone by 11beta-hydroxysteroid dehy...

Topics

Alternative Splicing
Genetic Variation
Humans
Organ Specificity
RNA, Messenger
Receptors, Mineralocorticoid

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