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Article

Human Mineralocorticoid Receptor Genomic Structure and Identification of Expressed Isoforms

1 Sept 1995

Abstract excerpt

Most of the known effects of aldosterone are mediated by the mineralocorticoid receptor, an intracellular receptor belonging to the steroid/thyroid hormone/retinoic acid receptor superfamily. We determined the genomic structure of the human MR (hMR) and identified 10 exons in the gene, including two exons (1 alpha and 1 beta) that encode different 5'-untranslated sequence. Expression of the two different hMR...

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Identifiers

PMID: 7673127
DOI: 10.1074/jbc.270.36.21016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human Mineralocorticoid Receptor Genomic Structure and Identification of Expressed IsoformsPMID 7673127Read ↗

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An alternatively spliced rat mineralocorticoid receptor mRNA causing truncation of the steroid binding domain.Semantic proximity Read ↗

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Lysine-Cysteine-Serine-Tryptophan Inserted into the DNA-Binding Domain of Human Mineralocorticoid Receptor Increases Transcriptional Activation by AldosteroneSemantic proximity Read ↗

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