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Article

Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.

The American journal of pathology - 1 Sept 2007

Sainte Marie Yannis, Toulon Antoine, Paus Ralf, Maubec Eve, Cherfa Aicha, Grossin Maggy, Descamps Vincent, Clemessy Maud, Gasc Jean-Marie, Peuchmaur Michel, Glick Adam, Farman Nicolette, Jaisser Frederic

Abstract excerpt

The mineralocorticoid receptor (MR) is a transcription factor of the nuclear receptor family, activation of which by aldosterone enhances salt reabsorption in the kidney. The MR is also expressed in nonclassical aldosterone target cells (brain, heart, and skin), in which its functions are incompl...

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Identifiers

PMID: 17675581
DOI: 10.2353/ajpath.2007.060991
PMCID: PMC1959477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17675581-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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