Article
Human mineralocorticoid receptor A and B protein forms produced by alternative translation sites display different transcriptional activities
1 Apr 2004
Abstract excerpt
OBJECTIVE: Aldosterone binds the mineralocorticoid receptor (MR) and is involved in the regulation of ionic transport, mainly sodium retention. MR is encoded by one single gene transcribed into various messengers that are thought to be translated into a unique 107 kDa protein. The aim of this study was to identify and characterize translation initiation variants of the human MR protein. METHODS: For this purpose...
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