Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of sulindac on sporadic colorectal adenomatous polyps.

Gut - 1 Mar 1997

Matsuhashi N, Nakajima A, Fukushima Y, Yazaki Y, Oka T

Abstract excerpt

BACKGROUND: Although sulindac is known to cause regression of colorectal adenomatous polyps in familial adenomatous polyposis, less is known about the effect of sulindac on sporadic adenomas. The precise mechanisms of these effects also remain to be determined. AIMS: Sulindac was given to patients with sporadic colorectal adenomatous polyps to evaluate its effects on them, and histological analysis was performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 9135523
DOI: 10.1136/gut.40.3.344
PMCID: PMC1027084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of sulindac on sporadic colorectal adenomatous polyps.PMID 9135523Read ↗

Relationship between APC genotype, polyp distribution, and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis.Semantic proximity Read ↗

Primary chemoprevention of familial adenomatous polyposis with sulindac.Semantic proximity Read ↗

Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis.Semantic proximity Read ↗

Does Mutated K-RAS Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?Semantic proximity Read ↗

Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.Semantic proximity Read ↗

Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.Semantic proximity Read ↗

The effect of sulindac on colon polyps: circumvention of a transformed phenotype--a hypothesis.Semantic proximity Read ↗

Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis.Semantic proximity Read ↗

Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell linesSemantic proximity Read ↗

Sulindac sulfone is most effective in modulating beta-catenin-mediated transcription in cells with mutant APC.Semantic proximity Read ↗

Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice.Semantic proximity Read ↗

Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.