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Article

Spm1, a stress-activated MAP kinase that regulates morphogenesis in S.pombe.

The EMBO journal - 17 Mar 1997

Zaitsevskaya-Carter T, Cooper J A

Abstract excerpt

A gene encoding a novel MAP kinase family member, Spm1, was isolated from the fission yeast Schizosaccharomyces pombe. Overproduction of Spm1 inhibits proliferation. Disruption of the spm1+ gene interferes with cell separation and morphogenesis. Under conditions of nutrient limitation, hypertonic stress or elevated temperature, spm1 delta cells grow as short branched filaments in which the cell walls and septa...

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Identifiers

PMID: 9135147
DOI: 10.1093/emboj/16.6.1318
PMCID: PMC1169729

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