Article
The CDK-activating kinase CAK1 can dosage suppress sporulation defects of smk1 MAP kinase mutants and is required for spore wall morphogenesis in Saccharomyces cerevisiae.
The EMBO journal - 17 Mar 1997
Wagner M, Pierce M, Winter E
Abstract excerpt
Mitogen-activated protein (MAP) kinase pathways are evolutionarily conserved kinase cascades that are required for the response of eukaryotic cells to a wide variety of environmental stimuli. MAP kinase pathways are also required for the execution of developmental and differentiative programs in a variety of cell and tissue types. SMK1 encodes a developmentally regulated MAP kinase in yeast that is required for...
Topics
- Alleles
- Calcium-Calmodulin-Dependent Protein Kinases
- Cyclin-Dependent Kinases
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Microscopy, Electron
- Mutation
- Phenotype
- Protein Serine-Threonine Kinases