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Article

The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 2005

Huang Linda S, Doherty Hugh K, Herskowitz Ira

Abstract excerpt

Spore formation in Saccharomyces cerevisiae involves the sequential deposition of multiple spore wall layers between the prospore membranes that surround each meiotic product. The Smk1p mitogen-activated protein (MAP) kinase plays a critical role in spore formation, but the proteins that interact...

Topics

Cell Wall
Down-Regulation
Genes, Fungal
Glucosyltransferases
Membrane Proteins
Mitogen-Activated Protein Kinases
Models, Biological
Mutation
Phenotype
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 16116083
DOI: 10.1073/pnas.0502324102
PMCID: PMC1194906

Genes

GSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16116083-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae.PMID 16116083Read ↗

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SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae.Semantic proximity Read ↗

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