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Article

Activation of the Smk1 mitogen-activated protein kinase by developmentally regulated autophosphorylation.

Molecular and cellular biology - 1 Feb 2013

Whinston Elizabeth, Omerza Gregory, Singh Amrita, Tio Chong Wai, Winter Edward

Abstract excerpt

Smk1 is a meiosis-specific mitogen-activated protein kinase (MAPK) in Saccharomyces cerevisiae that controls spore morphogenesis. Similar to other MAPKs, it is controlled by dual phosphorylation of its T-X-Y activation motif. However, Smk1 is not phosphorylated by a prototypical MAPK kinase. Here, we show that the T residue in Smk1's activation motif is phosphorylated by the cyclin-dependent kinase...

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Identifiers

PMID: 23207907
DOI: 10.1128/MCB.00973-12
PMCID: PMC3571338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activation of the Smk1 mitogen-activated protein kinase by developmentally regulated autophosphorylation.PMID 23207907Read ↗

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