Article
The Ras/cAMP pathway and the CDK-like kinase Ime2 regulate the MAPK Smk1 and spore morphogenesis in Saccharomyces cerevisiae.
Genetics - 1 Feb 2009
McDonald Christine M, Wagner Marisa, Dunham Maitreya J, Shin Marcus E, Ahmed Noreen T, Winter Edward
Abstract excerpt
Meiotic development (sporulation) in the yeast Saccharomyces cerevisiae is induced by nutritional deprivation. Smk1 is a meiosis-specific MAP kinase homolog that controls spore morphogenesis after the meiotic divisions have taken place. In this study, recessive mutants that suppress the sporulation defect of a smk1-2 temperature-sensitive hypomorph were isolated. The suppressors are partial function alleles of...
Topics
- Alleles
- Cell Cycle Proteins
- Cyclic AMP
- Fungal Proteins
- Gene Expression
- Genes, Fungal
- Glucose
- Intracellular Signaling Peptides and Proteins
- MAP Kinase Signaling System
- Meiosis
