Article
Defining the essential functional regions of the nucleoporin Nup145p.
Journal of cell science - 1 Apr 1997
Emtage J L, Bucci M, Watkins J L, Wente S R
Abstract excerpt
Studies of the essential nucleoporin Nup145p have shown that its depletion is coincident with a block in RNA export and that deletion of its amino-terminal domain results in clustering of nuclear pore complexes. To further define the functional domains of Nup145p, we have characterized a panel of nup145 mutants. Deletions from both the amino terminus and the carboxy terminus resulted in temperature sensitive...
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