Article
The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.
Molecular and cellular biology - 1 Jul 2004
Baï Siau Wei, Rouquette Jacques, Umeda Makoto, Faigle Wolfgang, Loew Damarys, Sazer Shelley, Doye Valérie
Abstract excerpt
We have characterized Schizosaccharomyces pombe open reading frames encoding potential orthologues of constituents of the evolutionarily conserved Saccharomyces cerevisiae Nup84 vertebrate Nup107-160 nuclear pore subcomplex, namely Nup133a, Nup133b, Nup120, Nup107, Nup85, and Seh1. In spite of rather weak sequence conservation, in vivo analyses demonstrated that these S. pombe proteins are localized at the...
Topics
- Active Transport, Cell Nucleus
- Animals
- Cell Division
- Cell Survival
- Chromosomes, Fungal
- Humans
- Macromolecular Substances
- Mutation
- Nuclear Pore
- Nuclear Pore Complex Proteins
- Open Reading Frames
- RNA, Messenger
- Recombinant Fusion Proteins
