Article
The yeast nucleoporin Nup188p interacts genetically and physically with the core structures of the nuclear pore complex.
The Journal of cell biology - 1 Jun 1996
Nehrbass U, Rout M P, Maguire S, Blobel G, Wozniak R W
Abstract excerpt
We have isolated a major protein constituent from a highly enriched fraction of yeast nuclear pore complexes (NPCs). The gene encoding this protein, Nup188p, was cloned, sequenced, and found to be nonessential upon deletion. Nup188p cofractionates with yeast NPCs and gives an immunofluorescent st...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Genes, Fungal
- Genes, Lethal
- Genetic Complementation Test
- Membrane Glycoproteins
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Nuclear Envelope
- Nuclear Pore
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins
- Sequence Analysis
- Sequence Analysis, DNA