Article
The yeast nucleoporin Nup188p interacts genetically and physically with the core structures of the nuclear pore complex.
The Journal of cell biology - 1 Jun 1996
Nehrbass U, Rout M P, Maguire S, Blobel G, Wozniak R W
Abstract excerpt
We have isolated a major protein constituent from a highly enriched fraction of yeast nuclear pore complexes (NPCs). The gene encoding this protein, Nup188p, was cloned, sequenced, and found to be nonessential upon deletion. Nup188p cofractionates with yeast NPCs and gives an immunofluorescent staining pattern typical of nucleoporins. Using immunoelectron microscopy, Nup188p was shown to localize to both the...
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