Article
The role of the integral membrane nucleoporins Ndc1p and Pom152p in nuclear pore complex assembly and function.
The Journal of cell biology - 8 May 2006
Madrid Alexis S, Mancuso Joel, Cande W Zacheus, Weis Karsten
Abstract excerpt
The nuclear pore complex (NPC) is a large channel that spans the two lipid bilayers of the nuclear envelope and mediates transport events between the cytoplasm and the nucleus. Only a few NPC components are transmembrane proteins, and the role of these proteins in NPC function and assembly remains poorly understood. We investigate the function of the three integral membrane nucleoporins, which are Ndc1p, Pom152p,...
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