Structure and assembly of the Nup84p complex.

doi:10.1083/jcb.149.1.41

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Article

Structure and assembly of the Nup84p complex.

The Journal of cell biology - 3 Apr 2000

Siniossoglou S, Lutzmann M, Santos-Rosa H, Leonard K, Mueller S, Aebi U, Hurt E

Abstract excerpt

The Nup84p complex consists of five nucleoporins (Nup84p, Nup85p, Nup120p, Nup145p-C, and Seh1p) and Sec13p, a bona fide subunit of the COPII coat complex. We show that a pool of green fluorescent protein-tagged Sec13p localizes to the nuclear pores in vivo, and identify sec13 mutant alleles that are synthetically lethal with nup85Delta and affect the localization of a green fluorescent protein-Nup49p reporter...

Topics

Alleles
Amino Acid Sequence
Cell Nucleus
Chromatography, Gel
Epistasis, Genetic
Fungal Proteins
Genes, Lethal
Membrane Proteins
Microscopy, Electron, Scanning Transmission
Molecular Sequence Data
Molecular Weight
Mutation
Nuclear Envelope
Nuclear Pore Complex Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Proteins

Porins

Protein Binding

RNA-Binding Proteins

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Identifiers

PMID: 10747086
DOI: 10.1083/jcb.149.1.41
PMCID: PMC2175103

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