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Article

FGF-stimulated outgrowth and proliferation of limb mesoderm is dependent on syndecan-3.

Developmental biology - 15 Apr 1997

Dealy C N, Seghatoleslami M R, Ferrari D, Kosher R A

Abstract excerpt

The outgrowth of the mesoderm of the developing limb bud in response to the apical ectodermal ridge (AER) is mediated at least in part by members of the FGF family. Recent studies have indicated that FGFs need to interact with heparan sulfate proteoglycans in order to bind to and activate their specific cell surface receptors. Syndecan-3 is an integral membrane heparan sulfate proteoglycan that is highly...

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Identifiers

PMID: 9133440
DOI: 10.1006/dbio.1997.8525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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