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Article

FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis.

Development (Cambridge, England) - 1 Feb 2008

Yu Kai, Ornitz David M

Abstract excerpt

Fibroblast growth factors (FGFs) are signals from the apical ectodermal ridge (AER) that are essential for limb pattern formation along the proximodistal (PD) axis. However, how patterning along the PD axis is regulated by AER-FGF signals remains controversial. To further explore the molecular me...

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Identifiers

PMID: 18094024
DOI: 10.1242/dev.013268

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SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094024-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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