Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple functions of fibroblast growth factors in vertebrate development.

Biochemical Society symposium - 1 Jan 1996

Abud H E, Skinner J A, Cohn M J, Heath J K

Abstract excerpt

The biological consequences of ectopic FGF-4 expression were examined in chimaeric mouse embryos prepared with ES cells constitutively expressing FGF-4. The embryos exhibit abnormalities of the limbs and the anterior central nervous system. The limb phenotype consisted of the induction of early phases of limb development along the lateral ridge between the definitive fore and hind limb buds, where normally no...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Chimera
Share to Extremities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Phenotype

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 8971338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple functions of fibroblast growth factors in vertebrate development.PMID 8971338Read ↗

Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function.Semantic proximity Read ↗

Normal limb development in conditional mutants of Fgf4.Semantic proximity Read ↗

Functions of FGF signalling from the apical ectodermal ridge in limb development.Semantic proximity Read ↗

Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning.Semantic proximity Read ↗

FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis.Semantic proximity Read ↗

A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowthSemantic proximity Read ↗

Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.Semantic proximity Read ↗

Molecular basis of vertebrate limb patterning.Semantic proximity Read ↗

Conserved mechanisms regulate outgrowth in zebrafish fins.Semantic proximity Read ↗

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless.Semantic proximity Read ↗

FGF2 promotes skeletogenic differentiation of cranial neural crest cellsSemantic proximity Read ↗

Fgf-4expression during gastrulation, myogenesis, limb and tooth development in the mouseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.