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Article

Use of gene-manipulated models to study the physiology of lipid transport.

Clinical and experimental pharmacology & physiology - 1 Jan 2000

Mortimer B C, Martins I, Zeng B J, Redgrave T G

Abstract excerpt

1. In vivo and in vitro gene-manipulated models were used to study the metabolism of chylomicron remnants. Transgenic mice expressing human apolipoprotein (Apo) A1 or E4, gene knockout mice deficient in ApoE or low density lipoprotein (LDL) receptors and antisense gene inhibition in HepG2 cells were used to evaluate the effect of gene manipulations on the metabolism of chylomicron remnants. 2. Mice transgenic for...

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Identifiers

PMID: 9131298
DOI: 10.1111/j.1440-1681.1997.tb01820.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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