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Article

Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice.

1 Jul 1997

Abstract excerpt

Apolipoprotein E (apoE) plays a key role in lipoprotein metabolism and may have other important biological functions. In humans, there are three common, naturally occurring isoforms of apoE that are associated with differences in lipid levels and atherosclerosis. However, the direct in vivo effects of the apoE isoforms on lipoprotein metabolism and atherosclerosis are not yet fully understood. To investigate the...

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Identifiers

PMID: 9202062
DOI: 10.1172/jci119501

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