Mechanisms of hepatic chylomicron remnant clearance.

Abstract excerpt

Experimental evidence suggests that chylomicron remnants, the carriers of dietary lipids, are highly atherogenic and that their postprandial plasma concentration is directly correlated with the progression of coronary artery disease. Much interest has therefore focused on elucidation of the various steps involved in uptake of these lipoprotein particles from the circulation. Recently, gene targeting has been...

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