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Article

Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice.

Journal of lipid research - 1 Aug 1998

Qiu S, Bergeron N, Kotite L, Krauss R M, Bensadoun A, Havel R J

Abstract excerpt

Mice lacking hepatic lipase have been reported to express mild hyperlipidemia characterized by increased concentrations of large high density lipoproteins, but normal concentrations of lipoproteins containing apolipoprotein B. Whereas hepatic lipase has been implicated in the clearance and processing of chylomicron remnants in rats, no such defect was found in these mice. We have further characterized the...

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PMID: 9717727

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