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Article

LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice.

Journal of lipid research - 1 Mar 2006

Kypreos Kyriakos E, Zannis Vassilis I

Abstract excerpt

We have used adenovirus-mediated gene transfer and bolus injection of purified apolipoprotein E (apoE) in mice to determine the contribution of LDL receptor family members in the clearance of apoE-containing lipoproteins in vivo and the factors that trigger hypertriglyceridemia. A low dose [5 x 10(8) plaque-forming units (pfu)] of an adenovirus expressing apoE4 did not normalize plasma cholesterol levels of...

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Identifiers

PMID: 16339113
DOI: 10.1194/jlr.M500322-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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