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Article

Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice.

Arthritis and rheumatism - 1 Dec 1998

Fleck M, Kern E R, Zhou T, Lang B, Mountz J D

Abstract excerpt

OBJECTIVE: To analyze Fas and tumor necrosis factor receptor I (TNFRI) apoptosis pathways in salivary gland inflammatory disease induced by murine cytomegalovirus (MCMV) infection. METHODS: Four different strains of mice (C57BI/6 [B6]-+/+, Fas-deficient B6-lpr/lpr, TNFRI-deficient B6-tnfr1(0/0), and B6-tnfr1(0/0)-lpr/lpr mice) were infected intraperitoneally with the Smith strain of MCMV (1 x 10(5) plaque-forming...

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PMID: 9870874
DOI: 10.1002/1529-0131(199812)41:12<2175::AID-ART12>3.0.CO;2-I

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