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Article

Expression of a MHC class II transgene determines both superantigenicity and susceptibility to mammary tumor virus infection.

The Journal of experimental medicine - 1 Oct 1993

Pucillo C, Cepeda R, Hodes R J

Abstract excerpt

Milk-borne mouse mammary tumor virus (MMTV) is a type B retrovirus that induces mammary carcinoma. Infectious MMTV, as well as genomically integrated mouse mammary proviruses, encode superantigens that are recognized by T cells that express appropriate T cell receptor V beta products. To determine the relationship between the superantigenic property of milk-borne MMTV and its in vivo infectivity, mice which were...

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Identifiers

PMID: 8397273
DOI: 10.1084/jem.178.4.1441
PMCID: PMC2191198

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Expression of a MHC class II transgene determines both superantigenicity and susceptibility to mammary tumor virus infection.PMID 8397273Read ↗

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