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Article

Mutational and functional analysis of the C-terminal region of the C3H mouse mammary tumor virus superantigen.

Journal of virology - 1 Jun 1998

Wrona T J, Lozano M, Binhazim A A, Dudley J P

Abstract excerpt

The mouse mammary tumor virus (MMTV) encodes within the U3 region of the long terminal repeat (LTR) a protein known as the superantigen (Sag). Sag is needed for the efficient transmission of milk-borne virus from the gut to target tissue in the mammary gland. MMTV-infected B cells in the gut express Sag as a type II transmembrane protein that is recognized by the variable region of particular beta chains (Vbeta)...

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Identifiers

PMID: 9573239
DOI: 10.1128/JVI.72.6.4746-4755.1998
PMCID: PMC110007

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Source receipt: pubmed, retrieved 7 Sept 2026.

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