Article
Mutational and functional analysis of the C-terminal region of the C3H mouse mammary tumor virus superantigen.
Journal of virology - 1 Jun 1998
Wrona T J, Lozano M, Binhazim A A, Dudley J P
Abstract excerpt
The mouse mammary tumor virus (MMTV) encodes within the U3 region of the long terminal repeat (LTR) a protein known as the superantigen (Sag). Sag is needed for the efficient transmission of milk-borne virus from the gut to target tissue in the mammary gland. MMTV-infected B cells in the gut expr...
Topics
- Amino Acid Sequence
- Animals
- DNA Mutational Analysis
- DNA, Viral
- Female
- Genes, Viral
- Mammary Tumor Virus, Mouse
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Molecular Sequence Data
- Mutation
- Rats
- Receptors, Antigen, T-Cell, alpha-beta
- Retroviridae Infections
- Sequence Alignment
- Superantigens
- Tumor Virus Infections