Article
A serum response factor-dependent transcriptional regulatory program identifies distinct smooth muscle cell sublineages.
Molecular and cellular biology - 1 Apr 1997
Kim S, Ip H S, Lu M M, Clendenin C, Parmacek M S
Abstract excerpt
The SM22alpha promoter has been used as a model system to define the molecular mechanisms that regulate smooth muscle cell (SMC) specific gene expression during mammalian development. The SM22alpha gene is expressed exclusively in vascular and visceral SMCs during postnatal development and is tra...
Topics
- Animals
- Base Sequence
- Binding Sites
- Cells, Cultured
- DNA
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Genes, Reporter
- Lac Operon
- Mice
- Mice, Transgenic
- Microfilament Proteins
- Molecular Sequence Data
- Muscle Development
- Muscle Proteins
- Muscle, Smooth
- Muscle, Smooth, Vascular
- Mutation