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Article

Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression.

Circulation research - 26 Oct 2007

Gan Qiong, Yoshida Tadashi, Li Jian, Owens Gary K

Abstract excerpt

There has been considerable controversy regarding the lineage relationship between smooth muscle cells (SMCs) and myofibroblasts, because they express a number of common cell-selective markers including smooth muscle (SM) alpha-actin. We have shown previously that MCAT elements within the SM alpha-actin promoter confer differential activity in cultured SMCs versus myofibroblasts. In the present study, to...

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Source

Identifiers

PMID: 17823374
DOI: 10.1161/CIRCRESAHA.107.154831

Genes

MCAT
TEF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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