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Article

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.

Developmental cell - 1 Jul 2006

Nishimura Go, Manabe Ichiro, Tsushima Kensuke, Fujiu Katsuhito, Oishi Yumiko, Imai Yasushi, Maemura Koji, Miyagishi Makoto, Higashi Yujiro, Kondoh Hisato, Nagai Ryozo

Abstract excerpt

Alteration in the differentiated state of smooth muscle cells (SMCs) is known to be integral to vascular development and the pathogenesis of vascular disease. However, it is still largely unknown how environmental cues translate into transcriptional control of SMC genes. We found that deltaEF1 is upregulated during SMC differentiation and selectively transactivates the promoters of SMC differentiation marker...

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PMID: 16824956
DOI: 10.1016/j.devcel.2006.05.011

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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