Article
Extension of the Replicative Life Span of Human Diploid Fibroblasts by Inhibition of the p33<sup><i>ING1</i></sup> Candidate Tumor Suppressor
1 Apr 1997
Abstract excerpt
Previous studies suggest that tumor suppressors may play significant roles in blocking the growth of cells during cellular senescence. We therefore studied the potential involvement of a novel growth inhibitor and candidate tumor suppressor gene called ING1, which we have cloned recently (I. Garkavtsev, A. Kazarov, A. Gudkov, and K. Riabowol, Nat. Genet. 14:415-420, 1996), in the process of cellular senescence....
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