Article
The role of the tumour suppressor p33 ING1b in human neoplasia.
Journal of clinical pathology - 1 Jul 2003
Nouman G S, Anderson J J, Lunec J, Angus B
Abstract excerpt
The inhibitor of growth (ING) genes (ING1-4) probably descend from tumour suppressor genes. ING1 was the first to be identified and later isolated using an approach to detect genes whose expression is suppressed in cancer. The others were isolated through homology and similarity searches in human and mouse databases. All members contain a plant homeodomain involved in macromolecule recognition. Apart from the...
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