Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymerase Delta in Eukaryotes: How is It Transiently Exchanged with Specialized DNA Polymerases During Translesion DNA Synthesis?

Current protein & peptide science - 1 Jan 2018

Liu Fengyu, Yang Yulong, Zhou Yajing

Abstract excerpt

Precise duplication of the human genome is constantly threatened by a variety of genotoxic insults. During S-phase, those damaged template bases could be overcome by DNA damage tolerance (DDT) pathways that bypass such obstacles instead of repairing them, allowing replicative machinery to resume beyond the offending lesions. Two distinct strategies of DDT, template switching and translesion DNA synthesis (TLS),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Polymerase III

Share to DNA Repair

Share to DNA Replication

Share to Eukaryota

Share to Protein Processing, Post-Translational

Share to Ubiquitination

Source

Identifiers

PMID: 29708067
DOI: 10.2174/1389203719666180430155625

Genes

DDT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymerase Delta in Eukaryotes: How is It Transiently Exchanged with Specialized DNA Polymerases During Translesion DNA Synthesis?PMID 29708067Read ↗

DNA polymerase delta in dna replication and genome maintenanceSemantic proximity Read ↗

Roles of DNA polymerases in replication, repair, and recombination in eukaryotes.Semantic proximity Read ↗

Translesion synthesis DNA polymerases and control of genome stability.Semantic proximity Read ↗

Error-prone repair DNA polymerases in prokaryotes and eukaryotes.Semantic proximity Read ↗

Translesion and Repair DNA Polymerases: Diverse Structure and MechanismSemantic proximity Read ↗

A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ.Semantic proximity Read ↗

DNA replication and repair bypass machines.Semantic proximity Read ↗

Repair and tolerance of DNA damage at the replication fork: A structural perspective.Semantic proximity Read ↗

Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex.Semantic proximity Read ↗

The expanding polymerase universe.Semantic proximity Read ↗

How DNA lesions are turned into mutations within cells?Semantic proximity Read ↗

Regulation and Modulation of Human DNA Polymerase δ Activity and FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.