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Gene expression regulation in trypanosomatids

24 Oct 2011

Abstract excerpt

Trypanosomatids are protozoan micro-organisms that cause serious health problems in humans and domestic animals. In addition to their medical relevance, these pathogens have novel biological structures and processes. From nuclear DNA transcription to mRNA translation, trypanosomes use unusual mechanisms to control gene expression. For example, transcription by RNAPII (RNA polymerase II) is polycistronic, and only...

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PMID: 22023440
DOI: 10.1042/bse0510031

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