Article
Genotype of cytochrome P450 2E1 and alcohol-related blood pressure elevation in Japanese men.
Blood pressure - 1 Mar 1997
Yamada Y, Ikai E, Honda R, Tsuritani I
Abstract excerpt
Three-hundred-and-sixty-seven unrelated Japanese male workers aged between 36 and 61 years were analysed for the genotypes of cytochrome P450 2E1 (CYP2E1), and the association with alcohol-related health effects including blood pressure (BP) elevation. Homozygous for the c1 (wild) gene was found in 204 men (55%), homozygous for the c2 (variant) gene in 17 (5%), and heterozygous in 146 (40%). Arithmetic means of...
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